Search on:
EDAR-ASSOCIATED DEATH DOMAIN PROTEIN
Descriptors Found:
1
Displaying:
1 .. 1
1 / 1
DeCS
Descriptor
English
:
Edar-Associated Death Domain Protein
Descriptor
Spanish
:
Proteína de Dominio de Muerte Asociada a Edar
Descriptor
Portuguese
:
Proteína de Domínio de Morte Associada a Edar
Tree Number:
D12.644.360.024.296.100
D12.644.360.024.500.061
D12.644.360.075.421.100
D12.776.157.057.024.100
D12.776.157.057.500.061
D12.776.476.024.375.100
D12.776.476.024.500.061
D12.776.476.075.421.100
Definition
English
:
A tumor
necrosis
factor receptor-associated factor that acts as a specific signaling adaptor protein for the
EDAR RECEPTOR
and plays an important role in ectodermal development. It binds to
edar receptor
via its C-terminal death domain region and to other specific TNF receptor-associated factors via its N-terminal domain. Loss of function of
edar-associated death domain protein
is associated with AUTOSOMAL RECESSIVE ANHIDROTIC
ECTODERMAL DYSPLASIA.
Entry Combination - descr/qualif
English
:
Edar-Associated Death Domain Protein
/
deficiency
use
Ectodermal Dysplasia, Hypohidrotic, Autosomal Recessive
History Note
English
:
2007(2002)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
52310
Unique Identifier:
D053362
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS